pentobarbital will decrease the level or impact of gefitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Watch Intently (1)pentobarbital will lower the extent or outcome of benzhydrocodone/acetaminophen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Warning when discontinuing CYP3A4 inducers that are coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone might boost and may lead to most likely lethal respiratory melancholy.
pentobarbital will decrease the level or result of bexarotene by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will decrease the level or result of ixabepilone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will reduce the extent or effect of mavacamten by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lower the extent or result of parecoxib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.
fentanyl transdermal and pentobarbital each increase sedation. Stay clear of or Use Alternate Drug. Limit use to patients for whom choice therapy options are insufficient
pentobarbital will reduce the level or outcome of lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with solid CYP3A4 inducers may result in lessened serum concentrations and loss of antimalarial efficacy
pentobarbital will reduce the level or result of larotrectinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Staying away from tissue extravasation in this method is essential as it has been identified to trigger tissue necrosis. Clinicians must prevent rapid IV injection since it may possibly end in respiratory despair, hypotension, and bronchospasm, amongst other adverse outcomes.
pentobarbital will minimize the extent or impact get more info of vincristine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.
pentobarbital will lower the level or result of dexamethasone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will reduce the extent or impact of piroxicam by influencing hepatic enzyme CYP2C9/10 metabolism. Minor/Importance Unidentified.
Following halting a CYP3A4 inducer, as the effects on the inducer drop, the fentanyl plasma concentration will maximize which could improve or lengthen both the therapeutic and adverse outcomes.